Metabolic alterations linked to T2D are very well characterised by epidemiological and research centered studies. The pathogenesis and progression of T2D is ascribed to 4 mechanisms; enhanced Highly developed glycation finish merchandise (AGE) development, elevated polyol pathway flux, activation of protein kinase C (PKC) isoforms, and improved hexosamine pathway flux[seven]. https://www.directivepublications.org/journal-of-diabetology-research/